a whole landscape of expression profiling in human brains for six neuropsychiatric disorders

Gene differential expression analysis and gene co-expression network analysis

Meta&Mega Analysis
WGCNA

Transcriptomic profiles of individual studies across six neuropsychiatric disorders

Autism Spectrum Disorder (ASD)
AccessionPMIDPlatform# of ASD Samples# of CTL Samples# of GenesBrain RegionCitation
GSE2852121614001Illumina HumanRef-8 v3.0 expression beadchip3638176863[1]
GSE38322(SubSeries of GSE38609, methyl)22984548Illumina HumanHT-12 V4.0 expression beadchip1718314262[2]
Bipolar Disorder (BD)
AccessionPMIDPlatform# of BD Samples# of CTL Samples# of GenesBrain RegionCitation
GSE5398731123247HG-U133P5153226013[3]
study5HG-U133P2118226011
GSE539216894394HG-U133A3235132522[4]
study2HG-U133A1127132521
study3HG-U133A2728132521
study7HG-U133A2932132521
GSE3597823147385HG-1_0st7394238232[5]
BrainGVEXnon-stranded, Illumina HiSeq200068233166601
Major Depressive Disorder (MDD)
AccessionPMIDPlatform# of MDD Samples# of CTL Samples# of GenesBrain RegionCitation
GSE5398731123247HG-U133P4953226013[3]
GSE5456524608543HG-U133P1516226011[6]
GSE5456724608543HG-U133P1413226011[6]
GSE5456824608543HG-U133P1313226011[6]
GSE5457124608543HG-U133P1011226011[6]
GSE5457224608543HG-U133P12 9226011[6]
GSE5457024608543HG-U133A712132521[6]
GSE5457524608543HG-U133A1110132521[6]
study2SMRI DatabaseHG-U133A1027132521
GSE5456224608543Illumina HumanHT-12 V3.0 expression beadchip99255311[6]
GSE5456324608543Illumina HumanHT-12 V3.0 expression beadchip2524255311[6]
GSE5456424608543Illumina HumanHT-12 V3.0 expression beadchip1920255311[6]
GSE3597823147385HG-1_0st2594238232[7]
Parkinson's Disease (PD)
AccessionPMIDPlatform# of PD Samples# of CTL Samples# of GenesBrain RegionCitation
GSE762117571925HG-U133P116226011[8]
GSE8397-GPL9616344956HG-U133A2817132523[9]
GSE8397-GPL9716344956HG-U133B2817104133[9]
GSE2029115965975HG-U133A1517132521[10]
GSE2016420926834HG-U133A64132521[11]
GSE2031420926834HG-U133A42132521[11]
GSE2692722864814Illumina HumanRef-8 v2.0 expression beadchip193181903[12]
GSE28894Illumina HumanRef-8 v2.0 expression beadchip5257157614
Alzheimer's Disease (AD)
AccessionPMIDPlatform# of AD Samples# of CTL Samples# of GenesBrain RegionCitation
GSE4835018832152HG-U133P75116226014[13]
GSE1268519295912HG-U133A55132521[14]
GSE3698023595620HG-1_0st2544238233[15]
GSE3726319937809HuEx-1_0-st78159271[16]
GSE2692722864814Illumina HumanRef-8 v2.0 expression beadchip180181903[12]
GSE2937823705665Illumina HumanHT-12 V3.0 expression beadchip3031378042[17]
ROSMAPnon-stranded, Illumina HiSeq6057162631
Schizophrenia (SCZ)
AccessionPMIDPlatform# of SCZ Samples# of CTL Samples# of GenesBrain RegionCitation
GSE4036HG-U133_Plus_21114226011
GSE1761219255580HG-U133_Plus_22521226011[18]
GSE2113822832356HG-U133_Plus_22728226011[19]
GSE2193521538462HG-U133_Plus_22117226011[20]
GSE5398731123247HG-U133_Plus_24353226013[3]
study5SMRI DatabaseHG-U133_Plus_21818226011
study2SMRI DatabaseHG-U133A1827132521
study3SMRI DatabaseHG-U133A2728132521
study7SMRI DatabaseHG-U133A3532132521
GSE3597823147385HG-1_0st9494238232[5]
GSE2692722864814Illumina HumanRef-8 v2.0 expression beadchip180181903[12]
BrainGVEXnon-stranded, Illumina HiSeq200090233166601